In some cases, they may not be available in all strengths or forms as the brand-name drug. Sulfasalazine is used to reduce inflammation and pain in rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), and ulcerative colitis (UC). Hydroxychloroquine renal toxicity Plaquenil eyewiki I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. Bi-Weekly blood draws were a total painful waste of time. Then began a very intense ringing in my ears. Discontinued Plaquenil twice a day, and dropped the SZS from 4 per day to 3. Reviews and ratings for sulfasalazine when used in the treatment of rheumatoid arthritis. 51 reviews submitted. User Reviews for Sulfasalazine to treat Rheumatoid Arthritis. "I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. O'Dell J R, Leff R, Paulsen G, Haire C, Mallek J, Eckhoff P J. et al Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine or a combination of the three medications results of a two year, randomized, double‐blind, placebo‐controlled trial. Arthritis Rheum 2002 46 1164–1170.1170 It’s used to decrease pain and swelling in the joints. In RA and JRA, the medication is used to treat people who haven’t responded to other therapies. Sulfasalazine taken with hydroxychloroquine Treatment of Rheumatoid Arthritis with Methotrexate Alone., Sulfasalazine User Reviews for Rheumatoid Arthritis at. Hydroxychloroquine 100 mg tabletDrugs used in chloroquine resistant malaria Patients should drink a lot of fluids ought to avoid taking it on an empty stomach or with antacids and while taking sulfasalazine. Hydroxychloroquine — Hydroxychloroquine, initially created as a treatment for malaria, was afterwards discovered to enhance outward indications of arthritis. DMARDs Disease-modifying antirheumatic drugs Side Effects. Combination therapy with sulfasalazine and methotrexate is more.. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Azulfidine Sulfasalazine is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis. Hydroxychloroquine is taken in tablet form, with or after food. Your doctor will advise you about the correct dose. Usually you will start on a full dose of 200–400 mg daily, and later your doctor may reduce this. When your condition is very well controlled you may be advised to take hydroxychloroquine only 2–3 times per week. Take hydroxychloroquine with a meal or a glass of milk. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Continue taking the medicine.