Chloroquine class of drug

Discussion in 'Canadian Pharmacy Drugs Online' started by Mr. Style, 13-Mar-2020.

  1. ezhurov XenForo Moderator

    Chloroquine class of drug


    According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance.

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    Chloroquine CQ, 2 was developed as a result of intense antimalarial drug development efforts in the USA during World War II, but the compound was familiar to Germans as early as 1934 under the name resochin. 176 The safety, efficacy, and low cost brought chloroquine to the front lines to treat malaria, and it was used extensively for almost. Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury. Apr 02, 2019 Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine.

    These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine).

    Chloroquine class of drug

    Hydroxychloroquine MedlinePlus Drug Information, Chloroquine - LiverTox - NCBI Bookshelf

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  6. The drug appeared to be responsible for a "rapid and effective speeding up of their healing process, and a sharp decrease in the amount of time they remained contagious". 70% of patients were "considered cured", compared with 12.5% of those who did not receive hydroxychloroquine and azithromycin combination.

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    Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin chloroquine and Sontochin 3-methyl-chloroquine. These compounds belonged to a new class of antimalarials, the four-amino quinolines. The German research went no further and the formula for Resochin was passed to a US sister company. Since Chloroquine phosphate tablets are known to concentrate in the liver, it should be used with caution in patients with hepatic disease or alcoholism or in conjunction with known hepatotoxic drugs. Central Nervous System Effects Chloroquine may increase the risk of convulsions in patients with a history of epilepsy. Drug Interactions

     
  7. Lapo4ka Well-Known Member

    Hydroxychloroquine belongs to a group of medicines known as antimalarials. Plaquenil side effects - kidney problems? - Symptoms. Does Plaquenil Cause Weight Gain - Ironstone Vineyards Hydroxychloroquine Side Effects Common, Severe, Long Term.
     
  8. asehndler User

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Phosphate Monograph for Professionals - Katzung pharm antimicrobials Flashcards Quizlet USMLE - NBME 18 - Questions and Answers - Discussions.
     
  9. buysssut New Member

    Skin Discoloration and Plaquenil - Arthritis Information Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  10. klenock New Member

    Plaquenil/ hydroxychloroquine Phoenix Rising ME / CFS Forums Feb 17, 2010 Anyone tried Plaquenil hydroxychloroquine? It's for reducing inflammation in autoimmune diseases. Because my clinic has messed up again with ordering the low dose naltrexone I'm supposed to be starting, I thought I'd get this out of my chest full of drugs and and give it a go while I'm.

    Plaquenil Uses, Dosage & Side Effects -