My rheumy thinks in the long run plaquenil will not be enough for me and I will have to go to the next step. My question is, if plaquenil doesn't work, what is the next step of medication? Is plaquenil porcine based Plaquenil help dry eyes Plaquenil low cost If the first anti-TNF you try doesn't work for you, your doctor will most likely try another one. If you still don't get relief, he may switch you to another type of biologic. These include With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. But the way my joint and skin pain has been going I may need bigger guns. Rheumy is very conservative with meds and always looks for the smallest dose possible and the least amount of meds. What if plaquenil doesn't work Seizure meds and plaquenil Epilepsy Foundation, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center Plaquenil 100mg What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Ask the Expert Plaquenil and Sjögren’s. Plaquenil. A medication for Lupus. Protecting your eyesight when taking Plaquenil Lupus Foundation of.. My rheumy thinks in the long run plaquenil will not be enough for me and I will have to go to the next step. My question is, if plaquenil doesn't work, what is the next step of medication? Rheumy is very conservative with meds and always looks for the smallest dose possible and the least amount of meds. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. If tranexamic acid doesn’t work for you, or if the side effects are bothersome, your doctor may suggest alternative medications for heavy periods. This might include NSAIDs, a hormonal IUD, oral.