One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine diabetes Chloroquine resistant malaria drug of choice Chloroquine phosphate price Images from Top left fundus photography Fd and fundus autofluorescence FAF, Top right en face optical coherence tomography OCT of the photoreceptor layers, and Bottom OCT B-scan of a 58-year-old woman with hydroxychloroquine retinopathy. Nomenclature of outer retinal hyper-reflective bands is a moving target, and will likely change again soonregardless of what they are called, if they appear abnormally reflective either they are damaged or misaligned. OCT, especially high-resolution spectral-domain SD-OCT, permits the visualization of all retinal layers, as well as the vitreous and the choroid. Localization of an abnormal finding to a specific layer of the retina often leads to a diagnosis that would not be otherwise possible. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct en face retina mesaurements plaquenil Retinal Physician - En Face OCT Imaging in Retinal Disorders, Normal OCT Anatomy - OCTMD Hydroxychloroquine mechanism of action in sleWhy is the drug hydroxychloroquineChloroquine breast cancerHydroxychloroquine at night Rationale for Screening. Hydroxychloroquine and CQ retinopathy are not reversible, and cellular damage may progress even after the drugs are stopped. When retinopathy is not recognized until a bull’seye appears, the disease can progress for years, often with foveal thinning and an eventual loss of visual acuity. Recommendations on Screening for Chloroquine and.. The ABCs of OCT. Hydroxychloroquine retinopathy A review of imaging. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing. Purpose To evaluate swept source optical coherence tomography angiography SS-OCTA in patients treated with hydroxychloroquine HCQ for more than 5 years and to compare results with the tests currently recommended for screening of HCQ retinopathy. Methods In this controlled pilot study, consecutive patients treated with HCQ for more than 5 years underwent SS-OCTA, SS-OCT B-scan and en-face C. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.