Collagen, a key component important of scar tissue, can in excess lead to hardened and thickened tissue in organs and joints. There is no cure for scleroderma, but available treatments can help to manage its symptoms and reduce its severity. Plaquenil and uctd Suicidal chloroquine poisoning Chloroquine phosphate mw Anti-malarial drugs, such as Plaquenil hydroxychloroquine, is often used to manage lupus and can also be effective in scleroderma. Plaquenil is thought to interfere with communication between immune cells, which can suppress the damaging effect of an overly active immune response without raising a patient’s risk of susceptibility to infections. Some medications, such as plaquenil and minocycline, can cause permanent dark skin plaques, which resemble black and blue marks similar to morphea scleroderma. Cosmetically, pigmentation differences can be covered up with corrective cosmetics, such as Dermablend. Drug-Induced Hyperpigmentation caused by Minocycline Minocin Antibiotic Localized scleroderma ICD-9-CM code 701.0 may be limited to the skin and deep tissues below the skin. Two subcategories of localized scleroderma both included in code 701.0 are as follows • Morphea — oval-shaped, thick patches appear on the skin, which are white in the middle with a purple border. These have been helpful in managing the symptoms of both systemic and localized scleroderma. For some scleroderma patients, medications used to treat malaria may be prescribed. Plaquenil localized scleroderma Scleroderma Management and Treatment Cleveland Clinic, Systemic Scleroderma Skin Involvement Hyperpigmentation. What are the long term side effects of plaquenilAralen cloroquinaSe pueden tomar aspirina y plaquenil juntosPlaquenil uses for lupusPlaquenil and tingling hands Localized scleroderma is an autoimmune disease in which the immune system causes inflammation in the skin. The inflammation can trigger connective tissue cells to produce too much collagen, a fibrous protein that is a major part of many tissues. Excess collagen can lead to fibrosis, which is like scarring. Localized Scleroderma Juvenile. Coding for Scleroderma. Scleroderma Skin Involvement Itching Pruritus. With localized scleroderma, usually only the skin is affected, but sometimes, muscles can be, too. Typically, people with localized scleroderma present with Raynaud’s phenomenon first, and weeks or even years later, they develop other symptoms that lead to the diagnosis of scleroderma. Localized scleroderma also known as morphea or linear scleroderma Two/thirds of those diagnosed with scleroderma have the localized form, which affects the skin and not the internal organs as detailed above. Localized scleroderma does NOT evolve into systemic scleroderma. About Scleroderma Scleroderma is a connective tissue disease that involves changes in the skin, blood vessels, muscles, and internal organs. It is a type of autoimmune disorder, a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue.