Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Chloroquine for typhoid Does plaquenil cause leg cramps In 2003, a novel mechanism was described wherein hydroxychloroquine inhibits stimulation of the toll-like receptor TLR 9 family receptors. TLRs are cellular receptors for microbial products that induce inflammatory responses through activation of the innate immune system. It alters your immune system, but as far as I know, it doesn't actually suppress it. Plus, if you have only been on it a month, it's probably not built up enough in your body to have much of an effect. I have actually been way HEALTHIER than ever since being on Plaquenil AND Methotrexate, which DOES suppress the immune system - go figure! The mechanism is unknown. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil immune system Do either hydroxychol/Plaquenil put you at risk for greater., Does Plaquenil supress the immune system? Hydroxychloroquine side effects heart ef 25Plaquenil and pregnancy category These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Plaquenil Hydroxychloroquine sulfate is a drug originally used to prevent or treat malaria. Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. This type of disease occurs when the body's immune system attacks its own healthy tissue. Several small and uncontrolled studies have examined the effects of chloroquine or hydroxychloroquine on immune activation. One study of 8 patients taking chloroquine but no concomitant antiretroviral therapy for 8 weeks reported a decrease from 8% to 5.5% in the percentage of memory CD8 cells expressing HLA-DR and CD38. Does that mean I have a suppressed immune system. Plaquenil probably won’t protect you from getting Covid-19, but it should make it less dangerous and shorten the lifespan. I hope that answers some questions. I have decided to take next week off and keep my kids home for the next week. It isn’t worth the risk, and I am lucky to have a.